Name: Yin, Jing

Degree: Ph.D.

Title: Professo)

Phone number: 86-18686759026

E-mail: yinjing20135@163.com

Address: Northeast Forestry University, Shaw (Yifu) Teaching Building, Room 201

Education and Training:

1997 – 2001: Northeast Agricultural University, Bachelor of Plant Science

2001 – 2004: Northeast Agricultural University, Master of Science in Crop Science

2004 – 2007: Northeast Agricultural University, Ph.D. in Molecular Biology

2007 – 2009: Northeast Forestry University, Postdoctoral Training in Forestry Science

2018.1-2018.12, Joint BioEnergy Institute (JBEI), Laurence Berkeley National Laboratory (Berkeley Lab), USA, Visiting scholar in Metabolic engineering and synthetic biology of natural products

Employment:

2019 up to now: Northeast Forestry University, Professor

2011 – 2018: Northeast Forestry University, Associate Professor

2009 – 2011: Northeast Forestry University, Lecturer

Honors and Awards:

2023: Honorary title of outstanding undergraduate tutor of NEFU

2020: Second Prize of Teaching Reform in Heilongjiang Province (5th)

2019: Second prize for teaching quality of NEFU

2019: Second Prize of Science and Technology in Heilongjiang Province(2th)

2018: The third prize of Science and Technology in Heilongjiang Province (3th)

2016: The third prize of Harbin Science and Technology Progress Award, the first place (1th)

Research Specialty:

Metabolism regulation and synthetic biology of Natural product, large-scale cultivation of medicinal plants and cell engineering utilization, functional microbial mining and utilization

Courses to Teach:

Undergraduates course: Metabolic Biology, Cell Engineering, Cell Biology, Biotechnology Thesis Writing and Literature Retrieval

Postgraduate course: Metabolism and Regulation of Active Substance

Extramural Appointments and Service:

Director, Natural Products Society of Heilongjiang

Executive Director, Bioengineering Society of Heilongjiang

Research Interest:

The metabolic regulation and molecular mechanism of anti-tumor active components terpenoids and phenols were studied in forest and medicinal plants. The main contents include the mining and identification of key functional genes of triterpenoids and phenolic synthesis pathways. The efficient synthesis and regulation of terpenoids in plant tissues and cells, including environmental factors, nutrients and signaling molecules, were studied. Transcriptome and metabolomics techniques were used to analyze the regulatory network of triterpenoid metabolism, and on this basis, synthetic biology techniques were used to synthesize anti-tumor active components efficiently in yeast, filamentous fungi and model plants. The endophytic fungi from resistant plants were isolated and identified, and the biological functions of endophytic fungi were explored, screened and utilized.

Funding:

(1) National Natural Science Foundation of China (32371840), (P.I.)

2024/01/01-2027/12/30

Title: Function and mechanism of birch BpNPR1\3 protein in regulating triterpene synthesis by mediating SA signaling pathway

(2) Heilongjiang Provincial Nature Foundation Key Project (ZD2023C004), (P.I.) 2023/07/01-2026/07/01

Title: Metabolic pathway analysis of Betulin acid, high-efficiency functional gene mining and green biomanufacturing,

(3)The 14th Five-Year National Key Research and Development Project (2021YFD22003030105) , (P.I.).

2021/12/01-2026/12/01

Title: Research on adaptive control technology of Drought and cold Resistance of Manchu Salix.

(4) Projects from enterprises YQLH09GJS10, (P.I.).

2019/09/01-2021/09/01

Title: Identification and high-value application of active Components of Chinese hemp,

(5). National Natural Science Foundation of China (31570589)

2016/01/01-2019/12/30

Title: Functions and regulatory mechanisms of b-HLH transcription factors in response to MeJA and SA induced birch triterpene synthesis,

(6). National Natural Science Foundation of China (31200428)

2013/01/01-2015/12/30

Title: Preliminary study on the regulatory effects of CAS, DS gene RNAi and FPS gene overexpression on triterpene metabolic flow in Betulae platyphylla.

Publications:

(1) Jie Yang, Ying Li, Yuqi Zhang , Li Jia , Lu Sun , Siyao Wang , Jialei Xiao, Yaguang Zhan, Jing Yin* , Functional identification of five CYP450 genes from birch responding to MeJA and SA in the synthesis of betulinic acid from lupitol, Industrial Crops and Products, https://doi.org/10.1016/j.indcrop.2021.113513,

(2) Jia-lei Xiao，Jian-Guang Sun，Bo Pang，Xin Zhou，Yuan Gong，Lichao Jiang，Luan Zhang，Xiaodong Ding*，Jing Yin*. Isolation and screening of stress-resistant endophytic fungus strains from wild and cultivated soybeans in cold region of china. Applied Microbiology and Biotechnology. 2021（1），DOI 10.1007/s00253-020-11048-2

(3) Jing Yin; Jie Yang; Hongsi Ma; Tian Liang; Ying Li; Jialei Xiao;Hongmei Tian; Zhiqiang Xu; Yaguang Zhan*; Expression characteristics and function of CAS and a new beta-amyrin synthase in triterpenoid synthesis in birch (Betula platyphylla  Suk.), Plant Science, 2020, 294(110433).

(4) Jing Yin, Ying Li, Chunxiao Li, Jialei Xiao, Jie Yang, Xin Li, Lu Sun, Siyao Wang, Hongmei Tian,Yaguang Zhan .Cloning, expression characteristics of a new FPS gene from Birch（Betula platyphylla suk.）and functional identification in triterpenoid synthesis, Industrial Crops & Products, 2020, DOI 10.1016/j.indcrop.2020.112591

(5) Jing Yin, Lu Sun, Ying Li, Jialei Xiao, Siyao Wang, Jie Yang, Ziyue Qu,Yaguang Zhan. Functional identification of BpMYB21 and BpMYB61 transcription factors responding to MeJA and SA in birch triterpenoid synthesis, BMC Plant Biology,2020（01）DOI：10.1186/s12870-020-02521-1

(6) Jing Yin, Xin Li, Yaguang Zhan*, Ying Li, Ziyue Qu, Lu Sun, Siyao Wang, Jie Yang, Jialei Xiao . Cloning and expression of BpMYC4 and BpbHLH9 genes and the role of BpbHLH9 in triterpenoid synthesis in birch. BMC Plant Biology ,2017,17:214 DOI 10.1186/s12870-017-1150-z.

(7) Jing Yin, Chunxiao Li，Yaguang Zhan*, Hongran Sun, Yuan Gong, Mengyan Zhang,Jialei Xiao. The Response of Physiological Characteristics, Expression of OSC Genes, and Accumulation of Triterpenoids in Betula platyphylla Sukto MeJA and SA Treatment. Plant Mol Biol Rep, 2016 34,2 ： 427–439，DOI 10.1007/s11105-015-0931-5

（8）Mengyan Zhang, Siyao Wang, Jing Yin*，Chunxiao Li,Yaguang Zhan, Jialei Xiao,Tian Liang, Xin Li, Molecular cloning and promoter analysis of squalene synthase and squalene epoxidase genes from Betula platyphylla Suk, Protoplasma，2016, 253, （5）：5 1347–1363，DOI 10.1007/s00709-015-0893-3.