Name: Lu, Lei
Degree: Ph.D.
Title: Associate Professor
Phone number: 86-451-8219-2073
E-mail: llu@nefu.edu.cn
Address: Northeast Forestry University, Shaw (Yifu)Teaching Building, Room 437
Education and Training:
1999 – 2004: Northeast Forestry University, Bachelor of Science in Environmental Science
2004 – 2007: Northeast Forestry University, Master of Science in Microbiology
2007 – 2010: Northeast Forestry University, Ph.D. in Forest Bioengineering
Employment:
2010 – 2013: Northeast Forestry University, Lecturer
2013 – present: Northeast Forestry University, Associate Professor
Research Specialty:
Microbiology, Molecular Biology, Biocatalysis
Courses to Teach:
Environmental Microbiology, Experiment of Microbiology
Research Interest:
My research interest is Environmental Microbiology, with the focuses on microbial laccase and its applications. My previous work included isolation of laccase-producing microorganisms, heterologous expression of laccase gene and characterization of the recombinant enzyme. Currently, my research team is working on the molecular modification of microbial laccases and their potential application in degradation of environmental pollutants.
Funding:
(1) The Fundamental Research Funds for the Central Universities (DL10BA09) (P.I.)
10/01/2010 – 09/30/2013,
Title: Heterologous expression of laccase gene fromBacillussp. inPichia pastorisand its application in dye decolorization
(2) National Natural Science Foundation of China (31200394) (P.I.)
01/01/2013 – 12/31/2015,
Title: Directed evolution of laccase fromBacillus licheniformisand its application in dye decolorization
Publications:
Chunlei Wang, Daizong Cui,Lei Lu, Nin Zhang, Hongyi Yang, Min Zhao, Shaojun Dai.Cloning and characterization of CotA laccase from Bacillus subtilis WD23 decoloring dyes. (2016)Annals of Microbiology. 66(1): 461-467.
http://dx.doi.org/10.1007/s13213-015-1128-8
Tian-Nv Wang,Lei Lu, Jing-Yao Wang, Teng-Fei Xu, Jun Li, Min Zhao.Enhanced expression of an industry applicable CotA laccase from Bacillus subtilis in Pichia pastoris by non-repressing carbon sources together with pH adjustment: recombinant enzyme characterization and dye decolorization. (2015)Process Biochemistry. 50: 97-103.
http://dx.doi.org/10.1016/j.procbio.2014.10.009
Biao Chen, Wen-Qi Xu, Xin-Ru Pan,Lei Lu.A novel non-blue laccase from Bacillus amyloliquefaciens: Secretory expression and characterization. (2015)International Journal of Biological Macromolecules. 76: 39-44.
http://dx.doi.org/10.1016/j.ijbiomac.2015.02.019
Lei Lu, Tian-Nv Wang, Teng-Fei Xu, Jing-Yao Wang, Chun-Lei Wang, Min Zhao.Cloning and expression of thermo-alkali-stable laccase of Bacillus licheniformis in Pichia pastoris and its characterization. (2013)Bioresource Technology. 134: 81-86.
http://dx.doi.org/10.1016/j.biortech.2013.02.015
Lei Lu, Min Zhao, Guo-Fu Li, Jun Li, Tian-Nv Wang, De-Bin Li, Teng-Fei Xu.Decolorization of synthetic dyes by immobilized spore from Bacillus amyloliquefaciens. (2012)Catalysis Communications. 26: 58-62.
http://dx.doi.org/10.1016/j.catcom.2012.04.024
Lei Lu, Min Zhao, Tian-Nv Wang, Li-Yan Zhao, Mei-Hui Du, Tai-Lun Li, De-Bin Li.Characterization and dye decolorization ability of an alkaline resistant and organic solvents tolerant laccase from Bacillus licheniformis LS04. (2012)Bioresource Technology. 115: 35-40.
http://dx.doi.org/10.1016/j.biortech.2011.07.111
Xu Han, Min Zhao,Lei Lu, Yanhong Liu.Purification, characterization and decolorization of bilirubin oxidase from Myrothecium verrucaria 3.2190. (2012)Fungal Biology. 116: 863-871.
http://dx.doi.org/10.1016/j.funbio.2012.05.003
Lei Lu, Min Zhao, Shu-Cheng Liang, Li-Yan Zhao, De-Bin Li, Bei-Bei Zhang.Production and synthetic dyes decolourization capacity of a recombinant laccase from Pichia pastoris. (2009)Journal of Applied Microbiology. 107: 1149-1156.
http://dx.doi.org/10.1111/j.1365-2672.2009.04291.x
Lei Lu, Min Zhao, Bei-Bei Zhang, Shu-Yu Yu, Xi-Jun Bian, Wei Wang, Yan Wang.Purification and characterization of laccase from Pycnoporus sanguineus and decolorization of an anthraquinone dye by the enzyme. (2007)Applied Microbiology and Biotechnology. 74: 1232-1239.
http://dx.doi.org/10.1007/s00253-006-0767-x
Lei Lu, Min Zhao, Yan Wang.Immobilization of laccase by alginate–chitosan microcapsules and its use in dye decolorization. (2007)World Journal of Microbiology and Biotechnology. 23: 159-166.
http://dx.doi.org/10.1007/s11274-006-9205-6
